H. Lee Moffitt Cancer Center & Research Institute

Paranasal Sinus and Nasal Cavity Cancer

Head and Neck Program

Stage I Paranasal Sinus and Nasal Cavity Cancer

Treatment depends on the type of cancer and where the cancer is found.

If cancer is in the maxillary sinus, treatment will probably be surgery to remove the cancer. Radiation therapy may be given after surgery.

If cancer is in the ethmoid sinus, treatment may be one of the following:

  • Radiation therapy, if the cancer cannot be removed with surgery.
  • Surgery followed by radiation therapy.
  • If cancer is in the sphenoid sinus, treatment is the same as for nasopharyngeal cancer and will probably be radiation therapy with or without chemotherapy. (Refer to the PDQ summary on Nasopharyngeal Cancer Treatment for more information.)

    If cancer is in the nasal cavity, treatment may be surgery, radiation therapy, or both.

    If the cancer is an inverting papilloma, treatment will probably be surgery. If the cancer comes back after surgery, patients may receive more surgery or radiation therapy.

    If the cancer is a melanoma or sarcoma, treatment will probably be surgery. For certain types of sarcoma, a combination of surgery, radiation therapy, and chemotherapy may be given.

    If the cancer is a midline granuloma, treatment will probably be radiation therapy.

    If cancer is in the nose (nasal vestibule), treatment may be surgery or radiation therapy.


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