H. Lee Moffitt Cancer Center & Research Institute

Oropharyngeal Cancer

Head and Neck Program

Stage Explanation

Stages of cancer of the oropharynx

Once cancer of the oropharynx is found, more tests will be done to find out if cancer cells have spread to other parts of the body. This is called staging. A doctor needs to know the stage of the disease to plan treatment. Imaging tests may be done, including special x-rays and an MRI (magnetic resonance imaging) scan, which uses a magnet, radio waves, and a computer to make a picture of the inside of the body. The following stages are used for cancer of the oropharynx.

Stage 0

Cancer is found only in cells lining the oropharynx. Stage 0 cancer is also called carcinoma in situ.

Stage I

The cancer is 2 centimeters (about ¾ inch) or smaller and has not spread outside the oropharynx.

Stage II

The cancer is larger than 2 centimeters, but not larger than 4 centimeters (about 1½ inches), and has not spread outside the oropharynx.

Stage III

Stage III is either of the following:

  • The cancer is larger than 4 centimeters and has not spread outside the oropharynx.
  • The cancer is any size and has spread to only one lymph node on the same side of the neck as the cancer. (Lymph nodes are small, bean-shaped structures found throughout the body. They help fight infection and disease.) The lymph node that contains cancer is 3 centimeters (just over one inch) or smaller.

Stage IVA

Stage IVA is either of the following:

  • The cancer has spread to tissues near the oropharynx, including the voice box, roof of the mouth, lower jaw, muscle of the tongue, or central muscles of the jaw. Cancer may have spread to one or more nearby lymph nodes, none larger than 6 centimeters (almost 2½ inches).
  • The cancer is any size, is only in the oropharynx, and has spread to one lymph node that is larger than 3 centimeters but no larger than 6 centimeters, or to more than one lymph node, none larger than 6 centimeters.

Stage IVB

Stage IVB is either of the following:

  • The cancer is found in a lymph node that is larger than 6 centimeters and may have spread to other tissues around the oropharynx.
  • Cancer surrounds the main artery in the neck or has spread to bones in the jaw or skull, to muscle in the side of the jaw, or to the upper part of the throat behind the nose; the cancer may have spread to nearby lymph nodes.

Stage IVC

In stage IVC, cancer has spread to other parts of the body; the tumor may be any size and may have spread to lymph nodes.

Recurrent

Recurrent disease means that the cancer has come back (recurred) after it has been treated. It may come back in the oropharynx or in another part of the body.


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