H. Lee Moffitt Cancer Center & Research Institute

Parathyroid Cancer

Head and Neck Program

Treatment Option Overview

How parathyroid cancer is treated

There are treatments for all patients with parathyroidcancer. Medical treatment to lower high blood levels of calcium caused by the disease is very important for all patients. In addition, three kinds of treatment are used:

  • Surgery (taking out the cancer).
  • Radiation therapy (using high-dosex-rays or other high-energy rays to kill cancer cells).
  • Chemotherapy (using anticancer drugs).
  • Surgery is the most effective treatment for parathyroid cancer. A doctor may remove the parathyroid gland (parathyroidectomy) and the half of the thyroid on the same side as the cancer (ipsilateralthyroidectomy). Nearby muscles, tissues and nerves may also be removed to prevent the cancer from spreading.

    Radiation therapy uses high-energy x-rays to kill cancer cells and shrink tumors.Radiation may come from a machine outside the body (external radiation therapy) or from putting materials that produce radiation (radioisotopes) through thin plastic tubes in the area where the cancer cells are found (internal radiation therapy).

    Chemotherapy uses drugs to kill cancer cells. Chemotherapy may be taken by pill, or it may be put into the body by a needle in the vein or muscle. Chemotherapy is called a systemic treatment because the drug enters the bloodstream, travels through the body, and can kill cancer cells outside the parathyroid gland.

    Treatment by stage

    Treatment for parathyroid cancer depends on the type and stage of the disease and the patient’s age and overall health.


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