H. Lee Moffitt Cancer Center & Research Institute

Nasopharyngeal Cancer

Head and Neck Program

Treatment Options by Stage

Stage I Nasopharyngeal Cancer

Treatment of stage I nasopharyngeal cancer is usually radiation therapy to the tumor and lymph nodes in the neck.

Stage II Nasopharyngeal Cancer

Treatment of stage II nasopharyngeal cancer may include the following:

  • Chemotherapy combined with radiation therapy.
  • Radiation therapy to the tumor and lymph nodes in the neck.

Stage III Nasopharyngeal Cancer

Treatment of stage III nasopharyngeal cancer may include the following:

  • Chemotherapy combined with radiation therapy.
  • Radiation therapy to the tumor and lymph nodes in the neck.
  • Radiation therapy followed by surgery to remove cancer-containing lymph nodes in the neck that remain or come back after radiation therapy.
  • A clinical trial of chemotherapy before, combined with, or after radiation therapy.

This summary section refers to specific treatments under study in clinical trials, but it may not mention every new treatment being studied. Information about ongoing clinical trials is available from the NCI Web site.

Stage IV Nasopharyngeal Cancer

Treatment of stage IV nasopharyngeal cancer may include the following:

  • Chemotherapy combined with radiation therapy.
  • Radiation therapy to the tumor and lymph nodes in the neck.
  • Radiation therapy followed by surgery to remove cancer-containing lymph nodes in the neck that remain or come back after radiation therapy.
  • Chemotherapy for cancer that has metastasized (spread) to other parts of the body.
  • A clinical trial of chemotherapy before, combined with, or after radiation therapy.
  • A clinical trial of new radiation therapy such as intensity-modulated radiation therapy.

This summary section refers to specific treatments under study in clinical trials, but it may not mention every new treatment being studied. Information about ongoing clinical trials is available from the NCI Web site.


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